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Histone Deacetylase (HDAC) Assay | ||||||||
Histone deacetylases (HDACs), also known as lysine deacetylases (KDACs), are a class of enzymes that remove acetyl groups from core histones (H2A, H2B, H3 and H4), thereby regulating gene expression.
These epigenetic enzymes influence the structure of chromatin, the protein-DNA complex that forms into chromosomes residing in the nucleus. By removing an acetyl group, HDACs enable the tightening of the chromatin structure i... |
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